Necrons are largely mechanical creatures, and as such it might seem inappropriate that weapons such as sniper rifles, which normally use poison to achieve their effect, and agonisers, which work against an enemy's nervous system, should be effective against them. In practice, anyone using these weapons against Necrons would make adjustments to counter the Necrons' defences, for example, using acid rounds instead of poisoned rounds or altering the charge from an agoniser to affect the Necrons' power systems. Because of this, Necrons do not receive any special immunities in this regard. In the Warhammer 40,000 universe there are many troops with an equal claim to special immunities, such as Tyranids and Daemons. It is therefore logical to assume that weaponry will keep pace to maintain fairness and avoid unnecessary complication.
Fighting the Necrons
Source: Codex: Necrons, p. 13